Research

Research is a major priority of the Washington University Division of Rheumatology.  Our laboratories are working to advance fundamental knowledge of human biology and disease, and our clinicians are conducting numerous clinical trials and epidemiological studies.

Ongoing basic and translational science efforts includes studies of complement, natural killer and other innate lymphoid cells, T-cell biology and mucosal immunology, chikungunya viral arthritis, lupus, vasculitis, innate and adaptive immunity, nanotherapies for rheumatoid arthritis, human genetics, host-pathogen interactions, and models of rare genetic diseases.  Clinical research efforts include clincial trials and epidemiological studies of rheumatoid arthritis, lupus, vasculitis, and rare genetic diseases.

Principal investigators in laboratories and those conducting clinical studies are listed below.

Basic and Translational Research Laboratories

• John P. Atkinson, MD (Complement and RVCL research)

Atkinson lab web site / RDRRC / RVCL research center / Publications

John Atkinson

• Dennis Hourcade, PhD (Complement and RVCL research)

Atkinson lab web site / RDRRC / RVCL research center / Publications

Dennis Hourcade

• Chyi Hsieh, MD (Autoimmunity, regulatory T cells, tolerance, and mucosal immunology)

Hsieh lab web site / RDRRC / Publications

Chyi Hsieh

• Alfred Kim, MD, PhD (Lupus translational research, B cell biology)

Kim lab web site / RDRRC / Publications

Al Kim

• Deborah Lenschow, MD (Chikungunya viral arthritis, interferons, autoimmunity)

Lenschow lab web site / RDRRC / Publications

Deb Lenschow

• M. Kathryn Liszewski, PhD (Complement and RVCL research)

Atkinson lab web site / RVCL research center / Publications

Kathy Liszewski

• Jonathan Miner, MD, PhD (Innate immunity, vasculitis, virology, SAVI, RVCL, rare diseases)

Miner lab web site / RVCL research center / Publications

Jonathan Miner

• Michael Paley, MD, PhD (Uveitis, scleritis, T-cell biology)

Yokoyama lab web site / Publications

Michael Paley

• Christine Pham, MD (Neutrophil proteases, nanomedicine for inflammatory arthritis)

Pham lab web site / RDRRC / Publications

Christine Pham

• Elisha Roberson, PhD (Genetic basis of hidradenitis suppurativa, other human diseases)

Roberson lab web site / RDRRC / Publications

Eli Roberson

• Xiaobo Wu, MD (Complement and RVCL research)

Atkinson lab web site / RVCL research center / Publications

Xiaobo Wu

• Wayne Yokoyama, MD (Natural killer cells, innate lymphoid cells, autoimmunity)

Yokoyama lab web site / RDRRC / Publications

Wayne Yokoyama

Clinical Research and Epidemiology

• John Atkinson, MD (RVCL clinical trials)

Clinical trials / Publications

John Atkinson

• Richard Brasington, MD (Scleroderma, rheumatoid arthritis, clinical trials)

Clinical trials / Publications

Rick Brasington

• Seth Eisen, MD (Epidemiology, former national director of VA Health Services Research and Development)

Clinical trials / Publications

Seth Eisen

• Amy Joseph, MD (Rheumatoid arthritis, hepatitis C, epidemiology)

Clinical trials / Publications

Amy Joseph

• Alfred Kim, MD, PhD (Lupus, epidemiology, clinical trials)

Clinical trials / Publications

Al Kim

• Jonathan Miner, MD, PhD (RVCL and vasculitis clinical trials)

Clinical trials / Publications

Jonathan Miner

• Michael Paley, MD, PhD (Uveitis, scleritis)

Clinical trials / Publications

Michael Paley

• Deborah Parks, MD (Rheumatoid arthritis, sarcoidosis, clinical trials)

Clinical trials / Publications

Deborah Parks

• Deepali Sen, MD (Lupus, clinical trials)

Clinical trials / Publications

Deepali Sen

• Prabha Ranganathan, MD, MSCI (Rheumatoid arthritis, epidemiology)

Clinical trials / Publications

Prabha Ranganathan